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Literature summary extracted from

  • Schaeffer, A.; Bronner, R.; Benveniste, P.; Schaller, H.
    The ratio of campesterol to sitosterol that modulates growth in Arabidopsis is controlled by sterol methyltransferase 2;1 (2001), Plant J., 25, 605-615.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.1.1.143 expression in Nicotiana tabacum Arabidopsis thaliana

Protein Variants

EC Number Protein Variants Comment Organism
2.1.1.142 additional information overexpression of SMT2 gene in a mutant strain leads to an accumulation of sitosterol and to an altered phenotype, some of the changes can be restored by brassinosteroid treatment, some cannot, sterol profile of wild-type and mutant plants Arabidopsis thaliana

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.1.1.142 S-adenosyl-L-methionine + cycloartenol Arabidopsis thaliana
-
 S-adenosyl-L-homocysteine + cyclolaudenol
-
 ?
2.1.1.143 S-adenosyl-L-methionine + 24-methylenelophenol Arabidopsis thaliana second methylation step of plant sterol biosynthesis S-adenosyl-L-homocysteine + 24-ethylidenelophenol
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.142 Arabidopsis thaliana
-
 3 isozymes encoded on SMT1, SMT2, SMT3
-
2.1.1.143 Arabidopsis thaliana
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.1.142 S-adenosyl-L-methionine + cycloartenol
-
 Arabidopsis thaliana S-adenosyl-L-homocysteine + cyclolaudenol
-
 ?
2.1.1.143 S-adenosyl-L-methionine + 24-methylenelophenol second methylation step of plant sterol biosynthesis Arabidopsis thaliana S-adenosyl-L-homocysteine + 24-ethylidenelophenol
-
 ?